Large Language Model

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Review clinical trials related to Large Language Model. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
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Status: Not yet recruiting

Large Language Models for Dental Radiology Report Generation From Structured Textual Data

The purpose of this observational methodological study is to evaluate whether large language models can transform structured dental radiology data into clear narrative radiology reports. Large language models are computer programs that can generate text from information provided to them. In this study, the input will consist of organized dental radiology findings, such as chart-style or diagram-based information about teeth and surrounding structures. Dental radiology reports are used by dentists and other health care providers to understand imaging findings and support clinical documentation. Preparing narrative reports may be time-consuming, and the wording of reports may vary between clinicians. This study will examine whether language-model-assisted report generation can produce reports that are complete, accurate, understandable, and clinically useful. The study will compare reports generated with support from large language models with traditionally prepared reports. Researchers will also assess how the wording of the prompt and selected model parameters influence report quality. In addition, the study will analyze errors and safety risks in generated reports and evaluate whether such a system could be practical in a dental radiology workflow. The language model will not make treatment decisions, and generated reports will be used for research evaluation only.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Hospital of the Ministry of Interior, Kielce, PolandUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Dental radiology records based on dental X-ray examination performed on the basi... [+2]

Records from patients with mixed dentition before completion of exfoliation [+4]

Status: Not yet recruiting

Large Language Model-Driven Personalization of Virtual Reality Interventions to Improve Pediatric Inpatient Experience and Reduce Needle Anxiety

Hospitalization strips pediatric patients of the environments, objects, and people that shape their daily lives. Hospitalized pediatric patients routinely experience painful procedures, psychological distress, boredom, and a disorienting loss of personal identity. These experiences measurably worsen anxiety, reduce cooperation with care, and diminish the quality of the inpatient experience for both patients and families.1-7 Immersive digital interventions, including VR and tablet-based experiences, have emerged as a promising class of tools for addressing these challenges. Prior studies from The Stanford Chariot Program have demonstrated that digitally delivered, patient-centered experiences can meaningfully reduce procedural anxiety and improve engagement in hospitalized children.8-12 Yet, an important limitation persists in these technologies - current digital interventions largely remain in one-size-fits-all formats. Every child receives the same content, regardless of who they are, what they love, or what makes them feel at home in the world. This design limits therapeutic relevance, constrains engagement, and represents a missed opportunity to engage children, reduce anxiety, and enhance their quality of life during hospital stays.

Participants needed: 20
Trial details
Age: 11-17Biological sex: AllType: InterventionalSponsor: Stanford UniversityUpdated: Jun 10, 2026
Eligibility criteria

English-speaking patients admitted for ≥24 hours

Acute medical instability [+4]

Status: Recruiting

Evaluating AI-Generated Plain Language Summaries on Patient Comprehension of Ophthalmology Notes Among English-Speaking Patients

This clinical trial is testing whether plain language summaries made by artificial intelligence help people understand their eye doctor's notes better. Adults receiving eye care at the Jules Stein Eye Institute will get either the usual medical notes or a note with the addition of an AI-generated summary that explains the information in simple, everyday words. Participants will then answer a short survey and receive a follow-up call to share how clear the information was, how well they understood their diagnosis and treatment, and whether they feel more confident about their care. The goal is to find out if these plain language summaries can make it easier for people to understand their eye care and improve communication between patients and health care providers.

Participants needed: 460
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of California, Los AngelesUpdated: Mar 5, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years English-speaking Receiving ophthalmology care at the Jules Stein...

Known cognitive impairments (e.g., dementia, intellectual disability) that would...