Status: Recruiting
The Role of the Free/Pedunculated Flap in Total Laryngectomy After (Chemo-)Radiotherapy Failure for Laryngeal Carcinoma: Impact on the Risk of Pharyngocutaneous Fistula (PCF)
Multicenter, prospective, randomized study aimed at evaluating the difference in risk of PCF after salvage laryngectomy in two groups of patients: one cohort treated with Total Laryngectomy (LT) with primary suture, a second group treated with LT and reinforcement by flap positioning with onlay technique (PMM, ALT)
Participants needed: 102
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Regina Elena Cancer InstituteUpdated: Jun 5, 2026Locations: 1
Eligibility criteria
pre (ChT-)RT staging: cT1/T2/T3 N0/N+; [+5]
STL extended to the pharynx and/or total pharyngeal laryngectomies; [+2]