Laser

8

Review clinical trials related to Laser. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparison of Er:YAG Assisted Laser Crown Lengthening Against Surgical Crown Lengthening

Crown lengthening is a clinical procedure that involves reshaping the gingiva, and sometimes bone, in order to expose more of tooth's structure. The procedures is performed for both functional and aesthetic reasons. In certain instances, this procedure is performed to This procedure is commonly performed for both functional and aesthetic reasons, such as to prepare a tooth for a crown or to enhance the appearance of a smile. Traditional crown lengthening techniques typically involve surgical methods that can be invasive, leading to extended recovery times and postoperative discomfort in this study we compare traditional versus the laser aided crown lengthening to compare the periodontal parameters in both cases.

Participants needed: 26
Trial details
Age: 20-70Biological sex: AllType: InterventionalSponsor: Gulf Medical UniversityUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Teeth indicated for crown lengthening procedure either in the maxillary or mandi... [+1]

Patients with uncontrolled diabetes mellitus. Uncontrolled diabetes mellitus dia... [+3]

Status: Recruiting

High-Energy Laser in the Conservative Treatment of Rhizarthrosis

Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis). It causes pain, deformity, limited movement and strength, joint instability, resulting in significant limitations in daily activities.Many conservative treatments, such as medications, therapeutic exercises, physical therapy, and orthoses, are effective for managing hand OA. For patients who do not respond to conservative treatments, surgical intervention will be necessary.

Participants needed: 42
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di BariUpdated: May 15, 2026Locations: 1
Eligibility criteria

arthrosis of the trapezoid-metacarpal with stage 1 or 2 of the Eaton-Littler rad... [+2]

rheumatoid arthritis or outcomes of trauma in the affected area, contra-indicati... [+1]

Status: Recruiting

Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy

this study was done to compare different laser frequencies on neuropathic outcomes in patients with Bell's palsy.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: Apr 9, 2026Locations: 1
Eligibility criteria

Eighty subjects from both genders diagnosed with Bell's palsy will be recruited... [+4]

We will exclude patients who had central nervous system pathology, sensory loss... [+4]

Status: Recruiting

Comparative Effectiveness of Long-Pulsed 1064-nm Nd:YAG and Fractional CO₂ Laser in Skin Rejuvenation

Skin rejuvenation is an effort to improve skin condition from the signs of skin aging. Skin aging is a complex biological process influenced by intrinsic and extrinsic factors, leading to changes in the epidermis and dermis, including decreased collagen characterized by dermal thinning, as well as alterations in skin appearance such as laxity and wrinkles. Laser therapy is one of the treatment modalities for skin rejuvenation, aiming to induce neocollagenesis and collagen remodeling, resulting in dermal thickening and improvement in skin appearance. Fractional CO₂ laser is an ablative laser considered the gold standard therapy for skin rejuvenation, whereas Long Pulsed (LP) Nd:YAG 1064 nm is a nonablative laser that is also used for skin rejuvenation. To date, there have been no studies evaluating the comparative effectiveness between fractional CO₂ laser and LP Nd:YAG 1064 nm for skin rejuvenation. Therefore, research comparing the effectiveness of fractional CO₂ laser and LP Nd:YAG 1064 nm for skin rejuvenation is needed, assessed based on dermal thickness, skin elasticity, wrinkles, and Global Aesthetic Improvement Scale scores.

Participants needed: 15
Trial details
Age: 30-59Biological sex: AllType: InterventionalSponsor: Universitas PadjadjaranUpdated: Mar 12, 2026Locations: 1
Eligibility criteria

Male and female patients with skin aging classified as Glogau scale II-III [+1]

Pregnant or breastfeeding women. [+9]

Status: Recruiting

Effect of Laser Acupoints on Fallopian Tube Obstruction

This study aims to determine the efficacy of laser acupoint therapy on treating fallopian tube obstruction.

Participants needed: 36
Trial details
Age: 20-35Biological sex: FemaleType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: Jan 20, 2026Locations: 1
Eligibility criteria

Women aged 20-35 years - nulliparous. [+6]

Currently pregnant or breastfeeding. [+7]

Status: Not yet recruiting

Evaluation of the Effect of Laser Therapy on Lateral Pterygoid Muscle in Patients With Wilke's Stage I and II Temporomandibular Disorders (TMD): Case Series Study

The purpose of this study will be to evaluate the effect of laser therapy on lateral pterygoid muscle in patients with Wilke's stage I and II temporomandibular disorders (TMD).

Participants needed: 25
Trial details
Age: 16-50Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jun 13, 2025
Eligibility criteria

Patients age between 16-50 years with no sex predilection. [+3]

Patients with previous temporo-mandibular surgeries. [+3]

Status: Not yet recruiting

Focal Laser Ablation in Prostate Cancer

To assess the effectiveness of MRI-US or PSMA PET/CT-U/S fusion-guided focal laser ablation (FLA) for the treatment of a localized, intermediate-risk prostate cancer in terms of short-term oncological \& functional outcomes.

Participants needed: 30
Trial details
Age: 45+Biological sex: MaleType: ObservationalSponsor: Ain Shams UniversityUpdated: Apr 8, 2025
Eligibility criteria

Prostate cancer visible on mpMRI or PSMA PET/CT and positive in the targeted bio... [+4]

Prostate cancer invisible on mpMRI or PSMA PET/CT but positive in the systematic... [+14]

Status: Not yet recruiting

Evaluating QoL and Postoperative Complications Using TEThA Technique in the Treatment of Tributary Veins

Endovenous laser thermoablation is a well-established alternative for the treatment of tributary veins. We believe that it is possible to improve the techniques described in the literature, aiming not only to allocate the laser fiber within the venous lumen, but mainly to transfix the vessel walls - a technique called TEThA (Transfixing Endovenous Thermal Ablation).

Participants needed: 20
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Nara Medeiros Cunha de Melo VasconcelosUpdated: Nov 1, 2024
Eligibility criteria

Not listed