Lateral Elbow Tendinopathy (Tennis Elbow)

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Review clinical trials related to Lateral Elbow Tendinopathy (Tennis Elbow). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) tested with a handheld device that slowly increases pressure on standard spots near the elbow and wrist; they say when it first becomes painful. To test the body's built-in anti-pain system (conditioned pain modulation, CPM), one hand is placed in ice water (the cold-pressor task) and PPT is measured again at set times (before, during, and after the cold stimulus) to see how much pain sensitivity changes and how long that change lasts. Both PPT reliability and CPM after effect are measured in this study. The study findings may help improve future assessment and treatment of musculoskeletal pain conditions.

Participants needed: 38
Trial details
Age: Up to 60Biological sex: AllType: InterventionalSponsor: The Hashemite UniversityUpdated: Jun 26, 2026Locations: 1
Eligibility criteria

Palpation of the lateral epicondyle [+5]

History of chronic pain conditions (e.g. fibromyalgia, irritable bowel [+6]

Status: Not yet recruiting

Mulligan Mobilization in Lateral Elbow Tendinopathy

The aim of this study is to investigate the short-, medium-, and long-term effects of Mulligan Mobilization with Movement (MWM) added to an exercise program on pain, functionality, and biomechanical parameters in individuals with lateral elbow tendinopathy, compared to sham mobilization and exercise-only interventions. The primary hypothesis is that the addition of true MWM to exercise will result in greater improvements in pain intensity, grip strength, pressure pain threshold, kinesiophobia, wrist joint position sense, and the mechanical properties of the extensor muscles compared to placebo (sham MWM) and exercise alone. This study is designed as a three-arm randomized placebo-controlled trial. A total of 45 participants will be allocated to one of three groups: MWM plus exercise, sham MWM plus exercise, and exercise alone. Assessments will be conducted at baseline, immediately post-intervention, and at 3- and 6-month follow-ups. The primary outcome measure is pain intensity. Secondary outcomes include functionality, grip strength, pressure pain threshold, kinesiophobia, wrist proprioception, and the mechanical properties of the extensor carpi radialis brevis muscle assessed using Myoton. This study aims to determine the effects of manual therapy independent of placebo and to evaluate the sustainability of these effects over time. Additionally, by objectively assessing the mechanical and proprioceptive characteristics of the muscle-tendon unit alongside clinical outcomes, the study is expected to provide a novel contribution to the literature. The findings are anticipated to enhance the understanding of the mechanisms underlying conservative treatment approaches in lateral elbow tendinopathy and to support evidence-based clinical decision-making.

Participants needed: 45
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Istanbul Kent UniversityUpdated: May 15, 2026Locations: 1
Eligibility criteria

Inclusion Criteria [+6]

History of surgery around the elbow [+8]

Status: Recruiting

Comparing the Effectiveness of the 'Think in Nerve Length and Layers' (TINLL) Approach to Traditional Treatment for Patients With Lateral Elbow Pain.

Lateral elbow pain can significantly limit people's ability to do the activities they want or need to do. We want to explore if one treatment technique is better than another for people with lateral elbow pain. You will be placed in a traditional treatment group or in a non-traditional treatment group. Your placement in the group will depend on past treatments you have had for this pain. Before you start treatment, you will be given four tests: 1) a grip strength test, 2) a pinch test, 3) a pain level survey, and 4) a functional survey. These four tests will take no longer than 15 minutes to complete. These four tests are common tests given to people with elbow pain. You will be given these four tests: * At the beginning, before you start treatment * At 2-weeks * At 4-weeks * At the end of your treatment Traditional treatment group: You will receive treatment 1x/week for 4-6 weeks. The traditional treatment group will consist of the following treatments: * stretching and strengthening of the wrist extensors * soft tissue work to the forearm muscles * joint mobilization at the elbow * rigid and elastic taping with focus on the wrist extensor muscles * ergonomic strategies * transcutaneous electrical nerve stimulation (TENS) * wrist splinting Non-traditional (TINLL) treatment group: You will receive treatment 1x/every 1-2-weeks for 4-6 weeks. The non-traditional (TINLL) treatment group will consist of the following treatments: * joint and tendon mobilization at the elbow * elastic tape for muscles and nerves * stretching/strengthening of the muscles at the elbow and upper arm * ergonomic strategies

Participants needed: 68
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of VermontUpdated: Feb 4, 2026Locations: 1
Eligibility criteria

understanding of English language; adults 18 years of age or older [+4]

subjects unable to cognitively follow directions [+4]

Status: Recruiting

Diagnostic Accuracy of the Clinical Tests and the Ultrasonography in Lateral Elbow Tendinopathy

Lateral elbow tendinopathy (LET) is the most common cause of elbow pain. Even though provocation tests such as Cozen's test, Mill's test or Maudsley test; musculoskeletal ultrasound or magnetic resonance imaging can be used for diagnosis, gold standard method is yet to be determined. Purpose of this study is to determine the sensitivity and specificity of clinical tests and ultrasonography in diagnosis of LET.

Participants needed: 100
Trial details
Age: 18-60Biological sex: AllType: ObservationalSponsor: Marmara UniversityUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

Patients aged 18-60 with unilateral elbow pain [+2]

History of rheumatologic diseases [+2]

Status: Recruiting

Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis

Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse. Even though, genetics factor related to tendinopathies were defined accompanying tendinopathies in patients with LE is yet to be studied. Madrid sonographic enthesitis index (MASEI) is an ultrasound based scoring system, developed for the evaluation of the enthesitis. Initially developed for ankylosing spondylitis, its usage has also become widespread in other musculoskeletal diseases. The aim of this study is to calculate the MASEI score in patients diagnosed with LE, and compare it to healthy volunteers.

Participants needed: 60
Trial details
Age: 18-60Biological sex: AllType: ObservationalSponsor: Marmara UniversityUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

Tenderness with palpation at the lateral epicondyle [+1]

History of rheumatologic diseases [+4]