LDL-C

2

Review clinical trials related to LDL-C. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Impact of the Corrie Lipids Digital Health Program on Lipid Optimization

The overall objective is to evaluate the effectiveness and implementation of the Corrie Lipids Program, a comprehensive digital health initiative designed to address critical gaps in lipid-lowering as a component of ASCVD treatment by delivering an intervention that combines a patient-facing smartphone app, clinician education and coaching, and seamless incorporation into clinical workflows. Researchers plan to assess this multicenter digital health initiative in approximately 1,000 adults with uncontrolled LDL-C and elevated ASCVD risk using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. The study will examine whether the program improves LDL-C goal attainment, app engagement, prescribing patterns, and LDL-C monitoring, while also identifying barriers and facilitators to implementation across sites.

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Mar 18, 2026Locations: 1
Eligibility criteria

Age ≥18 years [+5]

Motor, cognitive, auditory, or visual impairment limiting technology use [+5]

Status: Recruiting

Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?

The goal of this implementation trial is to learn if providing education to doctors and patients who have had a heart event works to prevent future heart problems. The main questions it aims to answer are: 1. Does educating the doctors in a health system improve how often patients in the hospital for a heart event have their cholesterol checked? 2. Can a "care champion" who calls patients who have been discharged from the hospital after a heart event help patients to achieve their cholesterol goals? Researchers will compare the number of people who achieve their cholesterol goals with the help of the care champion to the number of people who did so without the intervention to see if the care champion works to help patients lower their cholesterol. Participants will: Complete two 15 minute surveys over the phone - 1 at enrollment and 1 at the end of the study 6 months later.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years old [+3]

Determined to be highly unlikely to survive and/or to continue follow-up in that... [+1]