Status: Recruiting
Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia
The study is a monocentric, interventional study that evaluates the efficacy of allogeneic HLA-matched or haploidentical transplantation consisting of an irradiation-based conditioning regimen coupled with donor Treg/Tcon adoptive immunotherapy for high-risk acute leukemia patients.
Participants needed: 51
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University Of PerugiaUpdated: Mar 4, 2025Locations: 1
Eligibility criteria
AML patients [+16]
AML patients [+15]