Health Trials

LGMD2I

2

Review clinical trials related to LGMD2I. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

The purpose of this study is to evaluate the safety and tolerability of a single intravenous infusion of AB-1003 in adults diagnosed with limb girdle muscular dystrophy type 2I/R9 (LGMD2I/R9). Participants will be treated in sequential, dose-level cohorts. (Part 1)

Participants needed: 10
Trial details
Phase: Phase 1, Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: AskBio IncUpdated: Feb 20, 2026Locations: 6
Eligibility criteria

Male and female subjects aged 18 and 65 years with clinical diagnosis of LGMD2I/... [+3]

Significant cardiomyopathy as defined by echocardiogram (left ventricular ejecti... [+12]

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Status: Recruiting

Long-Term Development of Muscular Dystrophy Outcome Assessments

This is a 24-month, observational study of up to 1000 participants with Limb Girdle Muscular Dystrophy (LGMD), Myotonic Dystrophy Type 2 (DM2), and late onset Pompe disease (LOPD).

Participants needed: 1,000
Trial details
Age: 6-50Biological sex: AllType: ObservationalSponsor: Virginia Commonwealth UniversityUpdated: Nov 18, 2025Locations: 1
Eligibility criteria

Age between 6-50 years at enrollment [+3]

Any other illness that would interfere with the ability to undergo safe testing... [+1]

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