Limb Absence

2

Review clinical trials related to Limb Absence. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators

Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait. The purpose of this proposed investigation is to determine if there are substantial physical and psychological benefits to fitting lower functioning Veteran ambulators having transfemoral amputations with an MPK compared with a nonmicroprocessor-controlled knee (NMPK). Using a repeated-measures, cross-sectional experimental design, approximately 20 Veterans with unilateral, transfemoral amputations will be evaluated on two separate occasions at the Jesse Brown VA Medical Center or the Edward Hines, Jr. VA Hospital, first with their conventional NMPK and then again after a 2-month accommodation period with the College Park Icon MPK.

Participants needed: 20
Trial details
Age: 45-85Biological sex: AllType: InterventionalSponsor: VA Office of Research and DevelopmentUpdated: May 8, 2026Locations: 2
Eligibility criteria

Unilateral, transfemoral amputation (any etiology). [+7]

Bilateral leg amputations. [+1]

Status: Recruiting

A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation

Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait. The Ossur Power Knee is the only commercially-available MPK that uses a motor to provide active power generation during walking and other activities. The purpose of this proposed investigation is to perform and compare biomechanical evaluations of the Power Knee and Ossur Rheo XC, a passive MPK, during walking and other activities by prosthesis users. Furthermore, mobility between male and female subjects will be compared to determine if there are differences in prosthetic knee usage on the basis of sex.

Participants needed: 20
Trial details
Age: 45-75Biological sex: AllType: InterventionalSponsor: VA Office of Research and DevelopmentUpdated: Sep 9, 2025Locations: 1
Eligibility criteria

Unilateral, transfemoral amputation (any etiology). [+9]

Bilateral amputations [+1]