Low-grade Serous Ovarian Carcinoma (LGSOC)

1

Review clinical trials related to Low-grade Serous Ovarian Carcinoma (LGSOC). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)

The purpose of this study is to evaluate the efficacy of addition of letrozole to the standard maintenance therapy in subjects following a primary diagnosis of Estrogen-receptor (ER) positive high and low grade epithelial ovarian cancer (including fallopian tube and primary peritoneal cancer) and subsequent primary treatment surgery and chemotherapy. Half of the participants will receive to the standard maintenance treatment, letrozole, whilst the other half receives placebo. The study's primary hypothesis is that the treatment with letrozole increases progression free survival in comparison to the maintenance standard treatment (superiority trial).

Participants needed: 540
Trial details
Phase: Phase 3Age: 18+Biological sex: FemaleType: InterventionalSponsor: Swiss GO Trial GroupUpdated: Sep 29, 2025Locations: 53
Eligibility criteria

Patients must be ≥ 18 years of age [+8]

Progressive disease at the end of adjuvant treatment as defined in chapter 9.2.1... [+7]