Lumbar Spine Instability

3

Review clinical trials related to Lumbar Spine Instability. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions

The purpose of this single-blind, randomized, controlled study is to assess the efficacy of "informative text messages" vs "traditional handouts" provided to lumbar spine surgery patients post-operatively.

Participants needed: 224
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: May 8, 2026Locations: 1
Eligibility criteria

Primary lumbar fusion 1-4 levels [+6]

Prior lumbar fusions [+5]

Status: Recruiting

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve to demonstrate the efficacy of the addition of regional analgesic techniques in reducing post-operative opioid requirements in patients undergoing common lumbar spinal surgical procedures.

Participants needed: 125
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: John O'TooleUpdated: Feb 17, 2026Locations: 1
Eligibility criteria

Age 18-80 [+2]

Opioid tolerant at the time of the surgical procedure--defined as consuming grea... [+7]

Status: Recruiting

Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial

Symptomatic lumbar spinal stenosis is the most common indication for spinal surgery. However, more than one-third of the patients undergoing surgery for lumbar stenosis report dissatisfaction with the results. On the other hand, conservative treatment has shown positive results in some cases. This trial will compare the outcomes of surgical versus non-surgical treatment for lumbar stenosis.

Participants needed: 200
Trial details
Age: 50-85Biological sex: AllType: InterventionalSponsor: University of Roma La SapienzaUpdated: Feb 12, 2024Locations: 1
Eligibility criteria

Age 50-85 years. [+3]

Degenerative deformity with Cobb angle >20°. [+7]