Lymph Node Dissection

5

Review clinical trials related to Lymph Node Dissection. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Radical Nephroureterectomy With vs Without Template Lymph Node Dissection in High-Risk Upper Tract Urothelial Carcinoma (T-LND UTUC)

The goal of this clinical trial is to learn if adding a template lymph node dissection (TLND) to the standard surgery for upper tract urothelial cancer (UTUC) can improve patient survival and prevent the cancer from recurrence. The main questions it aims to answer are: Do patients who receive standard surgery with LND live longer without their cancer returning? Is adding LND safe, and how does it affect surgery-related complications? Researchers will compare the group receiving standard surgery plus LND to the group receiving standard surgery alone to see if adding LND is more effective. Participants will: Be randomly assigned to one of the two surgical groups. Undergo their assigned surgery and recover in the hospital. Attend regular follow-up visits for checkups and scans for 5 years to monitor for cancer recurrence, with the possibility of long-term follow-up extending to 10 years.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Tianjin Medical University Second HospitalUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Signed written informed consent form (ICF). [+11]

Previous receipt of any anti-tumor therapy for UTUC, including chemotherapy, rad... [+18]

Status: Not yet recruiting

Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block in Patients Undergoing Breast Cancer Surgery

This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Rhomboid Intercostal Block in patients undergoing Breast Cancer Surgery With Axillary Lymph Node Dissection. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire.

Participants needed: 60
Trial details
Age: 18-65Biological sex: FemaleType: InterventionalSponsor: Antalya City HospitalUpdated: May 11, 2026Locations: 1
Eligibility criteria

Female patients aged 18-65 years [+5]

Refusal to participate [+8]

Status: Not yet recruiting

The Value of Near-Infrared Fluorescence Imaging in the Protection of the Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy

The goal of this clinical trial is to learn whether the application of indocyanine green near-infrared imaging system can accurately locate the recurrent laryngeal nerve (RLN) during lymph node dissection in esophageal cancer radical surgery, thereby reducing the risk of RLN injury. The main questions it aims to answer are: 1. Can preoperative intravenous administration of indocyanine green enable visualization of the RLN; 2. Does performing RLN dissection guided by near-infrared imaging system reduce the probability of RLN injury, leading to better clearance of RLN lymph nodes and improved RLN protection rates? Researchers will compare whether indocyanine green was intravenously administered preoperatively to assess intraoperative RLN visualization. Participants in the study group will receive intravenous indocyanine green at a dose of 5mg/kg 24 hours before surgery. All patients will be monitored for RLN injury-related complications postoperatively, and RLN injury status will be objectively assessed via laryngoscopy one week post-operation.

Participants needed: 144
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Fujian Medical University Union HospitalUpdated: Feb 12, 2026Locations: 1
Eligibility criteria

Age between 18 and 75 years at the time of diagnosis (excluding 18 and 75); [+4]

Allergy to ICG or iodine; [+13]

Status: Recruiting

Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm

The study investigated the efficacy and safety of a selective lymph node strategy (no lower mediastinal lymph node dissection for upper lobe tumors and no upper mediastinal lymph node dissection for lower lobe tumors) in patients with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter cT1N0M0 infiltrating NSCLC, aiming to more accurately assess the prognosis of the selective lymph node dissection strategy for nodes with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter.

Participants needed: 684
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Fudan UniversityUpdated: Aug 12, 2025Locations: 1
Eligibility criteria

Volunteer to participate in a clinical study and be willing to follow and have t... [+8]

T1N0M0 with a clinical stage other than 0.5 < CTR < 1 and a diameter of ≤ 2 cm; [+4]

Status: Not yet recruiting

Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer

This study aims to explore the value of indocyanine green (ICG) in laparoscopic distal gastrectomy with lymph node dissection for early gastric cancer.The patients with early gastric adenocarcinoma (cT1, N-/+, M0) will be studied.

Participants needed: 180
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Fujian Medical UniversityUpdated: Jul 22, 2021Locations: 1
Eligibility criteria

Age from 18 to 75 years [+7]

Women during pregnancy or breast-feeding [+16]