Lymphoblastic Leukemia, Acute, Childhood

2

Review clinical trials related to Lymphoblastic Leukemia, Acute, Childhood. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia

The objective of this study is to assess the safety and efficacy of anti-CD7 CAR T-cells in patients with refractory or relapsed T-lineage acute lymphoblastic leukemia (T-ALL).

Participants needed: 20
Trial details
Phase: Phase 1Age: 6-65Biological sex: AllType: InterventionalSponsor: National University Hospital, SingaporeUpdated: Sep 14, 2021Locations: 1
Eligibility criteria

Minimum level of pulmonary reserve defined as Grade ≤ 1 dyspnoea and oxygen satu... [+5]

Failure to meet any of the inclusion criteria [+8]

Status: Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia.

The objective of this study is to assess the safety and efficacy of a immunophenotype-adapted approach using CAR T-cells in patients with high-risk, refractory or relapsed B-lineage acute lymphoblastic leukemia (B-ALL).

Participants needed: 40
Trial details
Phase: Phase 1Age: 6-80Biological sex: AllType: InterventionalSponsor: National University Hospital, SingaporeUpdated: Sep 9, 2021Locations: 1
Eligibility criteria

Patients who are unable to tolerate standard chemotherapy due to significant tox... [+7]

Failure to meet any of the inclusion criteria. [+8]