Status: Recruiting
MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing
This is a single arm pilot study for patients with hematologic malignancies receiving unrelated or haploidentical related mobilized peripheral stem cells (PSCs) using the CliniMACS system for alpha/beta T cell depletion plus CD19+ B cell depletion with individualized ALC-based dosing of ATG to study impact on engraftment, GVHD, and disease free survival
Participants needed: 40
Trial details
Age: 0-25Biological sex: AllType: InterventionalSponsor: Medical College of WisconsinUpdated: May 13, 2026Locations: 1
Eligibility criteria
Patient age < 25 years. Both genders and all races eligible. [+21]
Patients who do not meet disease, organ, or infectious criteria. [+5]