Health Trials

Lymphoma, Large B-Cell, Diffuse (DLBCL)

2

Review clinical trials related to Lymphoma, Large B-Cell, Diffuse (DLBCL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

This study is a Phase 1 dose-escalation and dose-confirmation study to evaluate the safety and antitumor activity of UB-VV111. The study will enroll patients with relapsed/refractory large B-cell lymphoma (LBCL) and chronic lymphocytic leukemia (CLL).

Participants needed: 106
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Umoja BiopharmaUpdated: May 28, 2026Locations: 8
Eligibility criteria

18 years or older [+7]

Women who are pregnant or breastfeeding [+8]

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Status: Not yet recruiting

A Study to Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell Malignancies

This is an investigator-initiated, open-label, single-arm, dose-escalation and dose-expansion study to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of MTM-H-001 in adult participants with relapsed/refractory (R/R) B-cell malignancies.

Participants needed: 69
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Male or female, aged 18 - 75 years old (inclusive); [+12]

B-NHL participants with a history of Richter's transformation of chronic lymphoc... [+15]

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