Macromastia

2

Review clinical trials related to Macromastia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

NPWT Reduction Mammaplasty

In this prospective, randomized, split-body control trial, we aim to compare complications, patient-reported outcomes, and cost differentials following reduction mammaplasty with prophylactic closed incision negative pressure wound therapy versus standard adhesive dressing.

Participants needed: 92
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Medstar Health Research InstituteUpdated: Oct 27, 2025Locations: 1
Eligibility criteria

Female patients [+3]

Younger than 18 years of age [+19]

Status: Recruiting

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 30cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 30cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.

Participants needed: 128
Trial details
Phase: Phase 4Age: 13-25Biological sex: AllType: InterventionalSponsor: Connecticut Children's Medical CenterUpdated: May 29, 2025Locations: 2
Eligibility criteria

Female [+3]

Patients with history of substance use disorder or "chronic pain" defined as pai... [+8]