Status: Recruiting
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
The primary goal of this Phase I study is to determine the maximum tolerated dose of oncolytic adenovirus mediated double suicide-gene therapy in combination with fractionated stereotactic radiosurgery in patients with recurrent high-grade astrocytoma undergoing resection.
Participants needed: 18
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Henry Ford Health SystemUpdated: Dec 16, 2025Locations: 1
Eligibility criteria
Subjects with radiologic evidence of intracranial recurrence or progression of a... [+16]
Acute infection. Acute infection is defined by any viral, bacterial, or fungal i... [+10]