Malignant Pleural Mesothelioma, Advanced

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Review clinical trials related to Malignant Pleural Mesothelioma, Advanced. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

CT-95 in Advanced Cancers Associated With Mesothelin Expression

This is a Phase 1a/1b, first-in-human (FIH), open-label, multi-center dose escalation and expansion study of the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor activity of single-agent CT-95 in subjects with advanced (recurrent, unresectable, or metastatic) cancers associated with MSLN expression.

Participants needed: 70
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Context Therapeutics Inc.Updated: Jun 12, 2026Locations: 9
Eligibility criteria

ECOG 0 or 1 [+3]

Uncontrolled significant active infection or any medical or other condition that... [+3]

Status: Recruiting

Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma

The purpose of this study is to evaluate the efficacy and safety of Oncolytic Adenovirus(H101) combined with PD-1 inhibitor in patients with advanced malignant pleural mesothelioma who have previously been resistant to advanced PD-1 inhibitors.

Participants needed: 15
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Tianjin Medical University Second HospitalUpdated: Sep 11, 2023Locations: 1
Eligibility criteria

Age 18-75 years old (including boundary values), regardless of gender. [+4]

Physicians participating in the study believe that patients may not be able to p... [+2]