Status: Available
Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
The objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s), including but not limited to KRAS, NRAS, HRAS, BRAF, MEK, and ERK mutations who have incomplete response to or have exhausted available therapies. Ulixertinib is available for treatment as monotherapy or in combination with other clinically tolerable agent(s), conditionally approved by the drug manufacturer.
Trial details
Age: 12+Biological sex: AllType: Expanded AccessSponsor: xCuresUpdated: Jun 4, 2026Locations: 26
Eligibility criteria
In the opinion of the treating physician, the patient has exhausted or has inade... [+7]
Patient is already participating in or qualifies for and is able to enroll in a... [+9]