Health Trials

Mature B-cell Non-Hodgkin Lymphoma

2

Review clinical trials related to Mature B-cell Non-Hodgkin Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

The purpose of this study is to evaluate the safety and efficacy of glofitamab, as monotherapy and in combination with a standard chemoimmunotherapy regimen: rituximab, ifosfamide, carboplatin, and etoposide (R-ICE) in pediatric and young adult participants with relapsed and refractory (R/R) mature B-cell non-Hodgkin lymphoma (B-NHL).

Participants needed: 65
Trial details
Phase: Phase 1, Phase 2Age: 6-30Biological sex: AllType: InterventionalSponsor: Hoffmann-La RocheUpdated: Jul 2, 2026Locations: 30
Eligibility criteria

Age 6 months to < 18 years at the time of signing Informed Consent for Cohort A... [+9]

Isolated CNS disease of mature B-NHL without systemic involvement, and primary C... [+14]

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Status: Recruiting

Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents

The purpose of this study is to test whether intensive chemotherapy combined with early, adequate, and intensive use of Rituximab for aggressive B-NHL in children and adolescents can improve the EFS and OS compared with the historical study CCCG-BNHL-2015.

Participants needed: 87
Trial details
Phase: Phase 2, Phase 3Age: Up to 18Biological sex: AllType: InterventionalSponsor: Children's Cancer Group, ChinaUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

Histology or cytologically confirmed mature B-cell NHL/AL(Burkitt, DLBCL, PMLBL,... [+2]

Follicular lymphoma, MALT and nodular marginal zone are not included into this t... [+5]

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