Maxillary Transverse Deficiency

2

Review clinical trials related to Maxillary Transverse Deficiency. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Maxillary Expansion Methods on Nasomaxillary Structures

Maxillary transverse deficiency is an orthodontic anomaly characterized by the upper and lower dental arches being incompatible due to insufficient width of the maxilla. This condition typically manifests with clinical symptoms such as crossbite, crowding of teeth, and impaired respiratory function. Genetic factors, early primary tooth loss, mouth breathing, thumb sucking, and abnormal swallowing are among the causes of maxillary narrowing. Treatment options vary depending on the patient's age and the degree of suture closure. In pediatric and adolescent patients, rapid (RPE) or slow (SPE) orthodontic expansion can be achieved with palatal expansion appliances. However, in adult patients, due to the less flexible bone structure of the maxilla, methods such as surgically assisted expansion (SARME) or mini-screw-assisted expansion (MARPE) are preferred. Recent studies have shown that MARPE can be effective as a non-surgical alternative in young adults and can provide direct skeletal expansion without damaging the teeth.

Participants needed: 30
Trial details
Age: 15+Biological sex: AllType: InterventionalSponsor: Merve KulaksızUpdated: Jan 8, 2026Locations: 1
Eligibility criteria

Diagnosis of maxillary transverse deficiency. [+2]

Severe facial deformities or craniofacial syndromes. [+5]

Status: Recruiting

3D Evaluation of Maxillary Expansion Methods

This controlled prospective clinical trial aims to evaluate the effectiveness of different maxillary expansion methods in children with maxillary transverse deficiency. A total of 60 participants will be included: 20 patients will receive Invisalign Palatal Expander (IPE), 20 will receive acrylic cap splint Rapid Maxillary Expansion (RME), and 20 will serve as an untreated control group. Three-dimensional (3D) intraoral and extraoral scans will be taken at the end of expansion, at 3 months, and at 6 months. Primary outcomes include maxillary arch width, first molar angulation, palatal surface area, and palatal volume. Secondary outcomes include soft tissue changes in the facial region. This study provides a direct comparison between a traditional and a modern digital expansion method, generating evidence for clinical decision-making in pediatric orthodontics.

Participants needed: 60
Trial details
Age: 6-12Biological sex: AllType: InterventionalSponsor: Büşra Zeynep YörükUpdated: Dec 4, 2025Locations: 1
Eligibility criteria

Children aged 6-12 years [+2]

Systemic diseases affecting growth, bone metabolism, or craniofacial development [+4]