Metabolic-dysfunction-associated Fatty Liver Disease (MAFLD)

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Review clinical trials related to Metabolic-dysfunction-associated Fatty Liver Disease (MAFLD). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Linzhi Jianghuang Fufang Huoxue Anshen Capsule for Non-alcoholic Fatty Liver

This is a randomized, double-blinded, placebo-controlled clinical trial aimed at evaluating the efficacy and safety of Linzhi Jianghuang Fufang Huoxue Anshen Capsule (LJF) for non-alcoholic fatty liver.

Participants needed: 180
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Hong Kong Baptist UniversityUpdated: Jun 9, 2026
Eligibility criteria

1) Age between 18 and 65 years (inclusive); [+5]

1) Excessive alcohol intake (converted pure alcohol > 210 g per week for men, >... [+19]

Status: Recruiting

Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly

This study compares the effectiveness of the dietary supplement Gepaktiv with standard medications (UDCA and Ademetionine) in patients with fatty liver disease (MAFLD) and liver enlargement (hepatomegaly). Key points: * Participants will receive either Gepaktiv, UDCA, or Ademetionine for 15 days * Doctors will monitor liver health through blood tests and ultrasound scans * The study will check if Gepaktiv helps improve liver function as effectively as standard treatments. Main measurements: * Changes in liver enzyme levels (ALT, AST) * Reduction in liver size * Improvement in fat accumulation (steatosis) measured by FibroScan This research may provide evidence for a new natural option to support liver health.Data analysis will be done by an independent biostatistics

Participants needed: 90
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Phenomen PharmaUpdated: Jul 23, 2025Locations: 1
Eligibility criteria

Age 18 to 65 years [+7]

Liver cirrhosis or hepatocellular carcinoma [+6]