Health Trials

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

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Review clinical trials related to Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

The study will assess the efficacy and safety of 2 dose regimens of pegozafermin compared to placebo for the treatment of liver fibrosis stage F2 or F3 in adult participants with MASH.

Participants needed: 1,350
Trial details
Phase: Phase 3Age: 18-80Biological sex: AllType: InterventionalSponsor: 89bio, Inc.Updated: Jul 13, 2026Locations: 361
Eligibility criteria

Males or non-pregnant females aged between 18 and 80 years (inclusive) at time o... [+2]

Chronic liver diseases other than MASH [+4]

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Status: Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

The study will assess the efficacy and safety of 2 dose regimens of pegozafermin compared to placebo for the treatment of liver fibrosis stage F2 or F3 in adult participants with MASH.

Participants needed: 1,350
Trial details
Phase: Phase 3Age: 18-80Biological sex: AllType: InterventionalSponsor: 89bio, Inc.Updated: Jun 4, 2026Locations: 349
Eligibility criteria

Males or non-pregnant females aged between 18 and 80 years (inclusive) at time o... [+2]

Chronic liver diseases other than MASH [+4]

Read more