Metastatic Bone Disease

2

Review clinical trials related to Metastatic Bone Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Musculoskeletal Cancers Remote Monitoring and Care

This study aims to evaluate how walking stability and the ability to perform daily activities change during cancer treatment, and whether a smartwatch can detect these changes. The goal is to develop proactive, personalized tools that automatically monitor treatment response and predict potential complications. To support future implementation, the study will assess the feasibility of wearing a smartwatch for at least 12 hours per day, using a mobile application, and completing weekly questionnaires among patients with primary osteosarcoma or metastatic bone disease.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Case Comprehensive Cancer CenterUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

primary sarcoma or metastatic bone disease of the lower extremities or pelvis. [+2]

under 18 years of age at the time of study enrolment [+5]

Status: Recruiting

Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial

The goal of this clinical trial is to find out if removing and replacing part of the hip bone works better than using metal hardware to stabilize the bone in patients whose cancer has spread to the hip. The main questions are: 1. Does removing and replacing part of the bone work better than just stabilizing it with metal hardware? 2. Does removing and replacing the bone help reduce problems like cancer coming back or the metal hardware breaking? Researchers will compare two treatments: using metal rods and plates to stabilize the bone (internal fixation) versus removing part of the bone and possibly replacing the hip joint (resection and reconstruction) to see if the second option causes fewer problems. Participants will: * Be randomly assigned to one of two groups (internal fixation or resection and reconstruction). * Have one of the two surgeries based on which group they're in. * Go to follow-up appointments with the study doctor at 2 weeks, 6 weeks, 4 months, 6 months, 9 months, and 12 months after surgery.

Participants needed: 334
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Michelle Ghert, MDUpdated: Nov 10, 2025Locations: 6
Eligibility criteria

Life expectancy of at least 6 months [+4]

Lesions isolated to the femoral neck [+3]