Metastatic Malignant Solid Tumor

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Review clinical trials related to Metastatic Malignant Solid Tumor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

This is a Phase 1, open-label, multicenter, FIH study to evaluate the safety, tolerability, recommended Phase 2 dose (RP2D), PK/PD, and preliminary anti-tumor activity of ISM6331 in participants with advanced or metastatic malignant mesothelioma or other solid tumors. The study consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2).

Participants needed: 100
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: InSilico Medicine Hong Kong LimitedUpdated: Feb 17, 2026Locations: 10
Eligibility criteria

Male or female participants with age ≥18 years at the time of signing the inform... [+7]

Participants who have previously received a TEAD inhibitor. [+7]