Status: Not yet recruiting
Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study
This study aims to evaluate the use of node-sparing short-course radiotherapy combined with chemotherapy and Sintilimab, or chemotherapy alone, as neoadjuvant therapy for MSS-type locally advanced colon cancer. The goal is to explore the efficacy and safety of combining node-sparing short-course radiotherapy with chemotherapy and immunotherapy in the neoadjuvant setting for MSS-type locally advanced colon cancer, while also investigating the specific role of regional lymph nodes in tumor immunotherapy.
Participants needed: 140
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sir Run Run Shaw HospitalUpdated: Sep 19, 2024Locations: 2
Eligibility criteria
1. Patients willing to undergo neoadjuvant treatment. 2. Age ≥ 18 years. 3. Tumo... [+5]
1. History of other malignancies within the past 5 years. 2. Patients with metas...