Mild to Severe Crohns Disease

1

Review clinical trials related to Mild to Severe Crohns Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Preliminary Clinical Study on the Effect of Bacillus Subtilis on the Efficacy of Infliximab in Patients With Crohn's Disease

The goal of this clinical trial is to evaluate the effect of supplementing Bacillus subtilis compared to the control group on the efficacy of Infliximab in patients with Crohn's disease, and to summarize the role of supplementing Bacillus subtilis in the treatment of CD patients. Participants will be randomized into two groups: the Bacillus subtilis supplementation group and the control group. The patients in the Bacillus subtilis supplementation group received oral Bacillus subtilis capsules for 12 weeks. The control group did not receive additional intervention. Follow up once a week, and after the study, patients will come to the hospital to finish the evaluation indicators.

Participants needed: 24
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: The Third Xiangya Hospital of Central South UniversityUpdated: Aug 14, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years old, ≤ 75 years old; [+4]

Patients with ALT or AST exceeding the normal upper limit by more than twice, an... [+8]