Mitraclip

2

Review clinical trials related to Mitraclip. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Enhanced Valves Interventions and Safe AI Generated End Results

This non-interventional study aims to use artificial intelligence to improve the prediction of transcatheter heart valve interventions and optimize patient outcomes. It is based on the analysis of retrospective data from various specialized centers worldwide.

Participants needed: 21,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Montreal Heart InstituteUpdated: Oct 9, 2025Locations: 15
Eligibility criteria

five to ten image volumes at cardiac phases from 5% to 95% R-R [+7]

For TAVI group: Valve-in-valve procedures [+4]

Status: Not yet recruiting

Optimization of Heart Failure (HF) Medical Therapy After Transcatheter Valve Intervention (TVI) in Patients With Heart Failure With Reduced Ejection Fraction (HFrEF)

This trial is a single-center, open-label, randomized study designed to assess the impact of a rapid up-titration of Guideline-Directed Medical Therapy (GDMT) on heart failure with reduced ejection fraction (HFrEF) patients following transcatheter valve interventions. The study focuses on the efficacy of intensive treatment in decreasing NT-proBNP levels and improving patient outcomes, including survival rates and quality of life over a six-month period. Patients are closely monitored using both Point-of-Care technology and hospital-based assessments, with the goal of enhancing GDMT adjustments. This approach is compared to standard care to determine its potential benefits in the management of HFrEF post-valve intervention.

Participants needed: 160
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: IRCCS Ospedale San RaffaeleUpdated: Nov 4, 2024Locations: 1
Eligibility criteria

Hospital admission for severe symptomatic valve disease (aortic stenosis, mitral... [+8]

Age < 18 or > 85 years. [+18]