Moderate Thrombocytopenia

1

Review clinical trials related to Moderate Thrombocytopenia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

The main purpose of this study is to evaluate the efficacy of selinexor in JAKi-naïve participants with myelofibrosis (MF) and with normal platelet counts or with mild to moderate thrombocytopenia based on spleen volume reduction (SVR). Additional efficacy and safety parameters will also be assessed during the study.

Participants needed: 58
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Karyopharm Therapeutics IncUpdated: Feb 12, 2026Locations: 70
Eligibility criteria

A diagnosis of MF or post-ET or post-PV MF according to the 2016 World Health Or... [+11]

More than 10% blasts in peripheral blood or bone marrow (accelerated or blast ph... [+6]