Mood Disturbance

2

Review clinical trials related to Mood Disturbance. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms

The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a wait list to receive obsessive compulsive disorder-specific psychotherapy at an outpatient mental health clinic. This study will evaluate the influence of neurofeedback training on participant's overall sense of well-being, and additionally, whether any enhanced well-being is subsequently associated with positive changes in symptoms of obsessive compulsive disorder, post-traumatic stress, dissociation and other trauma-related mental health symptoms, emotional regulation, etc.

Participants needed: 20
Trial details
Age: 18-90Biological sex: AllType: InterventionalSponsor: Wayne State UniversityUpdated: Nov 12, 2025
Eligibility criteria

being a client placed on the clinic waitlist to receive exposure-response preven... [+4]

a lifetime history of significant untreated mental illness (not currently treate... [+9]

Status: Recruiting

Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance

The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main questions it aims to answer are: Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo. Participants will consume an 8-week supplement of both: * 1,330mg/day curcumin * 350mg/day epigallocatechin gallate (EGCG)

Participants needed: 64
Trial details
Phase: Early Phase 1Age: 18-50Biological sex: AllType: InterventionalSponsor: Auburn UniversityUpdated: Feb 14, 2025Locations: 1
Eligibility criteria

Adults age 18-50 [+3]

Currently consume curcumin or green tea daily [+2]