Health Trials

MSI-H or dMMR Advanced Solid Tumors

2

Review clinical trials related to MSI-H or dMMR Advanced Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

This Study Aims to Evaluate the Efficacy and Safety of QLS1317 in Patients With MSI-H/dMMR Advanced Solid Tumors.

The goal of this study aims to evaluate the efficacy and safety of QLS1317 in patients with MSI-H/dMMR advanced solid tumors who failed standard treatment.

Participants needed: 120
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Shanghai Qilu Pharmaceutical Research and Development Center LTDUpdated: Apr 27, 2026
Eligibility criteria

1. Have a history of allergy to any component of the study drug. 2. Oral medicat...

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Status: Recruiting

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

The goal of this clinical trial is to determine the most effective dose of EIK1005 that a person can take safely. Additionally, this study will test how well EIK1005 is tolerated alone and in combination with pembrolizumab in treating patients with advanced cancer.

Participants needed: 160
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Eikon TherapeuticsUpdated: Apr 8, 2026Locations: 10
Eligibility criteria

is ≥ 18 years of age at the time of signing the informed consent. [+6]

has not recovered (i.e., to Grade ≤ 1 or to baseline) from prior anti-cancer the... [+10]

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