Muscle Tear

3

Review clinical trials related to Muscle Tear. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of High Intensity Laser Therapy in Muscle Injuries

Muscle injuries are frequent traumatic events in daily life, particularly during sports. In sports, their incidence varies from 10% to 55% of total injuries. According to the Mueller Wohlfart classification, muscle injuries are classified into direct traumatic injuries (contusion-laceration) and indirect traumatic injuries, which are further divided into non-structural injuries (grade I and II) and structural injuries. Structural lesions are further divided into partial muscle lesions (grade III): 3 A, minor partial lesion, i.e. lesion of one or more primary bundles with a secondary bundle; 3 B, moderate partial lesion, i.e. lesion of at least one secondary bundle and with a rupture area \< 50% of the muscle surface; and (sub)total muscle injury (grade IV).

Participants needed: 24
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di BariUpdated: May 14, 2026Locations: 1
Eligibility criteria

presence of a grade III A muscle lesion of the lower limbs, according to the Mue... [+2]

previous muscle injuries or bone fractures of the lower limbs in the last 6 mont... [+4]

Status: Not yet recruiting

Thermal Therapies in the Treatment of Muscle Injuries

Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies. Amongst them, thermal therapies and especially cryotherapy modalities (Ice, Cold water immersion, perfused garments) have been extensively used on soft tissue injuries to reduce pain perception and decrease inflammation. However, recent findings in humans and in animals have reported conflictual results on the effects of cold on muscle regeneration. On the other hand, recent studies in humans suggest that passive heat exposure can impact positively muscle protein synthesis, mitochondrial content and muscle torque in injured, immobilized and healthy participants. Furthermore, preliminary results from our group have shown a faster removal of muscle damages from the muscle and suggest a better muscle regeneration after a localized heat exposure. As such, our preliminary results confirmed that local heating may represent a promising tool to accelerate muscle regeneration. This randomized controlled trial will investigate the therapeutic effect of two thermal interventions (Hot or cold-water immersion) in the management of acute lower limbs muscle injuries. 135 patients will be distributed in a counterbalanced way into 3 groups: Hot, Cold and Control. All the groups will receive the same physiotherapy treatment. The thermal intervention will consist in 10 sessions of either, 60-minute hot water bath (42°C) for the hot group or, 15-minute Cold water bath (12°C) for the cold group realized after the 10 first physiotherapy session. All thermal interventions will be performed after the testing and physiotherapy treatment.

Participants needed: 135
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: AspetarUpdated: Jul 1, 2025Locations: 1
Eligibility criteria

Participant reported a sudden event [+6]

Chronic condition, diabetes, or immune compromised state [+14]

Status: Recruiting

Achilles Tendon for the Treatment of Gluteus Medius Insufficiency

Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical treatment. Our hypothesis is that surgical treatment followed by physiotherapy increases hip function and reduces limping compared with non-surgical treatment with physiotherapy alone.

Participants needed: 44
Trial details
Age: 40-80Biological sex: AllType: InterventionalSponsor: Sahlgrenska University HospitalUpdated: Apr 8, 2025Locations: 1
Eligibility criteria

Persisting limping with positive Trendelenburg's sign for at least 12 months aft... [+3]

Neuromuscular disorders