Health Trials

Muscular Dystrophy in Children

2

Review clinical trials related to Muscular Dystrophy in Children. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)

The purpose of the study is to assess the efficacy, safety, and tolerability of zeleciment rostudirsen (DYNE-251) administered intravenously (IV) every 4 weeks to ambulatory Duchenne muscular dystrophy (DMD) participants, 4 to 18 years of age, with dystrophin mutations amenable to exon 51 skipping.

Participants needed: 90
Trial details
Phase: Phase 3Age: 4-18Biological sex: MaleType: InterventionalSponsor: Dyne TherapeuticsUpdated: May 27, 2026Locations: 1
Eligibility criteria

Ambulatory male with confirmed diagnosis of DMD and with a mutation in the dystr... [+2]

Receipt of ongoing immunosuppressive therapy (other than glucocorticoids) within... [+6]

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Status: Recruiting

Vasodilator and Exercise Study for DMD (VASO-REx)

Examining two strategies as potential adjuvant therapies for Duchenne muscular dystrophy (DMD); aerobic exercise training (to induce adaptations in skeletal muscle and improve cardiovascular health) and tadalafil, an FDA-approved vasodilator (to optimize blood flow and muscle perfusion which is impaired and often overlooked in DMD). Target: improved muscle function, vascular health, and DMD treatment.

Participants needed: 50
Trial details
Phase: Phase 2Age: 6+Biological sex: MaleType: InterventionalSponsor: University of FloridaUpdated: May 15, 2026Locations: 1
Eligibility criteria

Diagnosis of DMD confirmed by genetic report [+3]

Contraindication to a Magnetic resonance Imaging examination (e.g. severe claust... [+5]

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