Mycobacterium Abscessus Pulmonary Disease

2

Review clinical trials related to Mycobacterium Abscessus Pulmonary Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial

The goal of this clinical trial is to learn if a new combination antibiotic treatment (Arm D) works to treat a rare lung condition called mycobacterium abscessus pulmonary disease in people of any age and sex, when compared to the standard treatments. It will also learn about the safety of this new combination antibiotic treatment when compared to the standard treatments. The main questions it aims to answer are: * How well does Arm D treat mycobacterium abscessus pulmonary disease? * What side effects does Arm D cause when used to treat mycobacterium abscessus pulmonary disease? Researchers will compare Arm D to the current standard of care treatments to see if Arm D treats mycobacterium abscessus pulmonary disease better and if it will cause less side effects. Participants will: * Be screened and recruited to the FORMaT adaptive platform trial (NCT04310930) * Be given Arm D for 4 weeks or standard of care treatments for 6 weeks. * Be reviewed by the study doctors weekly for checkups and tests. * Provide respiratory samples (sample coughed up from the chest), respond to quality-of-life questionnaires, have CT lung scans and blood tests.

Participants needed: 300
Trial details
Phase: Phase 2Age: 12+Biological sex: AllType: InterventionalSponsor: The University of QueenslandUpdated: Mar 20, 2026
Eligibility criteria

Must meet eligibility criteria as per the FORMaT Master Protocol and Appendix A1... [+1]

Must not have any exclusion criteria as per the FORMaT Master Protocol and Appen... [+7]

Status: Recruiting

TCM as an Adjuvant Treatment in Mycobacterium Abscessus Pulmonary Disease

Chinese herbs can facilitate sputum culture conversion, promote lesion absorption, and enhance clinical symptoms and quality of life for patients with Mycobacterium abscessus pulmonary disease (MAB-PD). The investigators aimed to evaluate the efficacy of Chinese herbs as adjunct therapy to improve cure rates or reduce recurrence rates during the continuation phase of MAB-PD treatment.

Participants needed: 352
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Shanghai University of Traditional Chinese MedicineUpdated: Dec 22, 2025Locations: 8
Eligibility criteria

Patient diagnosed with Mycobacterium abscessus pulmonary disease; [+3]

Patients with a drug allergy to the investigational medication; [+11]