Mycoplasma Pneumoniae Pneumonia

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Review clinical trials related to Mycoplasma Pneumoniae Pneumonia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study

The goal of this clinical trial is to compare a placebo (a look-alike substance that contains no active drug) with a commonly used antibiotic in children with Mycoplasma pneumoniae (a specific bacterium) induced community-acquired pneumonia. The main question it aims to answer is: Is antibiotic treatment needed in Mycoplasma pneumoniae (a specific bacterium) induced pneumonia? Participants will receive either a placebo or a antibiotic treatment and track their symptoms and vital signs until they are healthy. Researchers will then compare the length of symptoms between the placebo and the antibiotic group.

Participants needed: 376
Trial details
Age: 3-17Biological sex: AllType: InterventionalSponsor: Christoph BergerUpdated: May 5, 2026Locations: 13
Eligibility criteria

Children aged 3-17 years (from 3rd up to 18th birthday) presenting to the emerge... [+6]

Contraindication to azithromycin: Documented allergy to azithromycin; cardiovasc... [+6]

Status: Not yet recruiting

Doxycycline vs. Macrolide for MRMP (DOMINO)

The goal of this clinical trial is to learn if doxycycline works to treat pneumonia in children. It focuses on children with Mycoplasma pneumoniae infection that may not respond to standard medicines. The main questions it aims to answer are: * Does doxycycline stop fevers faster than azithromycin? * Is doxycycline safe for children, specifically regarding tooth color changes? Researchers will compare doxycycline to azithromycin to see if doxycycline works better to treat this type of pneumonia. Participants will: * Take either doxycycline or azithromycin by mouth for 7 to 14 days. * Check their body temperature to see when their fever goes away. * Visit the hospital to check for any medical problems. * Have their teeth checked for color changes 28 days after starting the medicine.

Participants needed: 208
Trial details
Phase: Phase 4Age: 3-17Biological sex: AllType: InterventionalSponsor: Young June ChoeUpdated: Dec 29, 2025Locations: 14
Eligibility criteria

Age: 3 to 17 years at the time of enrollment. [+4]

Prior use of tetracyclines, macrolides, or quinolones for the current illness. [+4]