Health Trials

Myelodysplastic Syndrome Acute Myeloid Leukemia

2

Review clinical trials related to Myelodysplastic Syndrome Acute Myeloid Leukemia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

This is an open-label, Phase 1 study to determine the safety, tolerability, and efficacy of APL-4098 alone, and in combination with azacitidine, and in combination with azacitidine plus venetoclax for the treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS)/AML and MDS-excess blasts (EB).

Participants needed: 100
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Apollo Therapeutics LtdUpdated: Jun 1, 2026Locations: 9
Eligibility criteria

18 years or older [+7]

Certain prior therapies such as: received an allogeneic stem cell transplant wit... [+3]

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Status: Recruiting

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

The primary objective is to define the safety and tolerability of AB8939 in patients with AML by determining the dose-limiting toxicities, the maximum tolerated dose, and the recommended dose for dose expansion study.

Participants needed: 78
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: AB ScienceUpdated: Oct 2, 2025Locations: 10
Eligibility criteria

Patients with documented diagnosis of acute myeloid leukemia (AML) based on the... [+4]

Patients eligible to a standard of care [+17]

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