Nausea and Vomitting

2

Review clinical trials related to Nausea and Vomitting. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Co-Development and Validation of Colonic Symptom Pictograms for Young People

Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in colonic motility - the coordinated contractions that facilitate passage of stool through the colon and out of the body. Diagnosis of constipation is based upon the Rome IV criteria, which assess symptoms as reported or remembered over the previous 3 months. However, reporting symptoms experienced can be challenging for children and young people for many reasons, such as the overlap of sensations, including fullness, bloating, and discomfort, and an inability to recall or precisely distinguish and describe what they are feeling. This study intends to design, develop, and validate symptom pictograms for children aged 8-17 with colonic or lower gut symptoms.

Participants needed: 120
Trial details
Age: 8-17Biological sex: AllType: ObservationalSponsor: University of Auckland, New ZealandUpdated: Jan 13, 2026
Eligibility criteria

have lower gut or constipation symptoms, [+1]

Children and Young people with developmental or cognitive disorder that preclude... [+3]

Status: Not yet recruiting

Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.

The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women. Specifically, this study aim to compare intrathecal fentanyl with epidural fentanyl in order to determine whether the epidural route is associated with a lower occurrence and severity of pruritus. By clarifying these differences, the research seek to optimize analgesic strategies during labor while minimizing opioid-related side effects

Participants needed: 80
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: St. Justine's HospitalUpdated: Nov 26, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years [+4]

ASA score > 3 [+9]