Necrotic Pulp

2

Review clinical trials related to Necrotic Pulp. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques

Brief Summary Postoperative pain is a common complication following root canal treatment, particularly in necrotic teeth with asymptomatic apical periodontitis. Although obturation technique has been suggested as a contributing factor to postoperative discomfort, direct clinical comparisons between commonly used methods remain limited. Cold lateral condensation has traditionally been considered the standard obturation technique, while warm vertical obturation systems such as Obtura II have gained popularity due to their potential for improved adaptation of gutta-percha. This randomized controlled clinical trial aims to compare postoperative pain experience and treatment outcomes following cold lateral condensation and warm vertical obturation in single-rooted necrotic teeth. Postoperative pain will be assessed during the early healing period, along with patient-reported outcomes and short-term clinical and radiographic healing. The results of this study are expected to provide clinically relevant evidence to support evidence-based obturation technique selection and improve patient comfort in endodontic practice.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of JordanUpdated: Apr 2, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older. [+3]

Teeth diagnosed with symptomatic apical periodontitis. [+5]

Status: Not yet recruiting

Efficacy of Integrated Nano-technology in Revascularization of Immature Necrotic Teeth

This trial aims to study the effect of photoactivated disinfection using Diod laser (810 nm) to activate photosensitive nanoparticle chitosan as an endodontic irrigant versus sodium hypochlorite followed by saline and then EDTA 17% on 1) postoperative pain and 2) the success of revascularization in patients with necrotic immature maxillary anterior teeth using a randomized clinical trial design.

Participants needed: 20
Trial details
Biological sex: AllType: InterventionalSponsor: Minia UniversityUpdated: Oct 8, 2024
Eligibility criteria

o Immature necrotic maxillary incisor with open apex greater than 1 mm. [+4]

o Non-restorable teeth. [+3]