Neonatal Asphyxia

2

Review clinical trials related to Neonatal Asphyxia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy

Sovateltide (PMZ-1620; IRL-1620) is targeted to be used as a "Treatment for hypoxic-ischemic encephalopathy in neonates," which is a life-threatening condition. Sovateltide augments neuronal progenitor cell differentiation and better mitochondrial morphology and biogenesis to activate a regenerative response in the central nervous system. The only treatment for HIE is therapeutic hypothermia with limited success, and studies indicate that sovateltide may be beneficial in these patients.

Participants needed: 40
Trial details
Phase: Phase 2Biological sex: AllType: InterventionalSponsor: Pharmazz, Inc.Updated: Dec 31, 2025Locations: 4
Eligibility criteria

Either sex with ≥ 36 weeks of gestational age [+6]

Gestational age <36 weeks [+7]

Status: Not yet recruiting

Face Mask vs Laryngeal Mask in Neonatal Resuscitation

The goal of this single-centre interventional study without medication neither device (for procedure) is to improve training of health care personnel (physicians, nurses, and midwives) on neonatal resuscitation through manikin simulation. The main questions it aims to answer are: * Is it possible to compare the ease of use and speed of application of the laryngeal mask versus the face mask in ventilating the newborn during simulated manikin training? * What are the differences in the time required to achieve optimal skills in using the two masks? * What is health care personnel's level of confidence in using laryngeal mask versus face mask?

Participants needed: 150
Trial details
Biological sex: AllType: InterventionalSponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCSUpdated: Apr 30, 2025Locations: 1
Eligibility criteria

Healthcare Workers (physicians, nurses, and midwives) of the Neonatal Unit and D... [+1]

Healthcare Workers (physicians, nurses, and midwives) NOT of the Neonatal Unit a... [+1]