Status: Not yet recruiting
Exploratory Study on the Efficacy and Safety of Trastuzumab Rezetecan in the Treatment of HER2-Expressiong Advanced Solid Tumor
The goal of this clinical trial is to learn if Trastuzumab Rezetecan can treat advanced solid tumors with HER-2 expression in adult participants. The main question it aims to answer is: What is the objective response rate of Trastuzumab Rezetecan in adult patients with HER-2 expressed advanced solid tumors? Participants will receive intravenous infusion of Trastuzumab Rezetecan on Day 1 of each 21-day treatment cycle. The dosage is 4.8 mg/kg per cycle; participants with a body weight of 85 kg or above will receive a fixed dose of 408 mg every 3 weeks.
Participants needed: 15
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Haihua YuanUpdated: Jun 8, 2026
Eligibility criteria
Male and female participants aged 18 years or older. [+6]
Poorly controlled blood pressure (systolic blood pressure ≥ 150 mmHg or diastoli... [+13]