Nephritis, Lupus

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Review clinical trials related to Nephritis, Lupus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

The goal of this clinical trial is to learn if cenerimod, on top of regular treatment, works to treat active lupus nephritis in adults with systemic lupus erythematosus and active lupus nephritis. It will also learn about the safety of cenerimod. The main questions it aims to answer are: * Does cenerimod improve kidney function in participants? * What medical problems do participants have when taking cenerimod? Researchers will compare cenerimod to a placebo (a look-alike substance that contains no drug) to see how well cenerimod works when it is added to regular treatment. Participants will: * Take cenerimod or a placebo every day for 76 weeks (approximately 1.5 years), on top of regular treatment. * Visit the clinic every 1 to 3 months for checkups and tests.

Participants needed: 300
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Viatris Innovation GmbHUpdated: Jun 17, 2026Locations: 11
Eligibility criteria

Classification of systemic lupus erythematosus (SLE) made according to the 2019... [+1]

Active renal disease defined as urine protein/creatinine ratio ≥ 1 mg/mg, assess... [+35]