Neural Tube Defects

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Review clinical trials related to Neural Tube Defects. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Folic Acid Salt Study (FISFA Zambia)

Question: How effective is fortified iodized salt with folic acid (FISFA) in increasing serum and red blood cell folate in non-lactating, non-pregnant women of reproductive age in the country of Zambia who do not have active food fortification with a folic acid program? Participants will: * Consume salt with folic acid instead of their regular salt for 6 months * Have a blood draw 4 times * Fill out surveys

Participants needed: 250
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: University of Alabama at BirminghamUpdated: Jun 29, 2026Locations: 2
Eligibility criteria

Voluntary participation in the study [+4]

Pregnant or lactating

Status: Recruiting

Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases

The purpose of the study is to evaluate the safety and efficacy of devices used in patients undergoing fetoscopic neural tube defect repair.

Participants needed: 100
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Michael A BelfortUpdated: Dec 15, 2025Locations: 1
Eligibility criteria

Patients who elect to undergo fetoscopic neural tube defect repair

Patients who do not elect to undergo fetoscopic neural tube defect repair

Status: Recruiting

Fetoscopic Neural Tube Defect Repair

This is a single-arm prospective study to record maternal and neonatal outcomes on subjects who undergo fetoscopic repair of Neural Tube Defects (NTD) at Oregon Health \& Science University (OHSU). Fetoscopic repair will take place between 24 weeks 0 days and 27 weeks 6 days gestation. Surgical, post-operative, delivery, and neonatal outcomes will be collected.

Participants needed: 25
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Oregon Health and Science UniversityUpdated: Apr 27, 2025Locations: 1
Eligibility criteria

Maternal age 18 years or older [+8]

Multiple gestation [+17]

Status: Recruiting

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

The purpose of this study is to evaluate the feasibility of a fetoscopic surgical technique for antenatal correction of fetal myelomeningocele. Two surgical approaches will be utilized. The percutaneous approach will be offered to participants with a posterior placenta. The laparotomy/uterine exteriorization approach will be offered to participants regardless of placental location.

Participants needed: 12
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: USFetusUpdated: Nov 13, 2019Locations: 2
Eligibility criteria

Myelomeningocele (including myeloschisis) at level T1 through S1 with hindbrain... [+6]

Multiple gestation [+22]