Status: Recruiting
SPEARHEAD-3 Pediatric Study
This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.
Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 2-21Biological sex: AllType: InterventionalSponsor: USWM CT, LLCUpdated: Feb 9, 2026Locations: 10
Eligibility criteria
Subject has histologically confirmed diagnosis of any one of the following cance... [+5]
Positive for HLA-A*02:05 in either allele; or any A*02 having same protein seque... [+8]