Status: Recruiting
Lipid Infusions to Optimize Nutrition Trial
The purpose of this study is to identify survival free of bronchopulmonary dysplasia (BPD), fatty acid profiles, and early biochemical measures for oxidative stress comparing mixed oil lipid emulsion (MOLE) vs soybean oil-based lipid emulsion (SOLE) and to establish whether MOLE or SOLE is more effective in minimizing pulmonary outcomes, neonatal morbidities, long-term morbidity and mortality, and improving discharge growth and Bayley Scales of Infant Development Fourth Edition (BSID-IV) neurodevelopmental assessment at two years
Participants needed: 230
Trial details
Phase: Phase 2Age: 12-28Biological sex: AllType: InterventionalSponsor: The University of Texas Health Science Center, HoustonUpdated: Jul 13, 2026Locations: 1
Eligibility criteria
inborn <28 weeks gestational age (GA) or ≤1000g birth weight (BW) [+1]
Infants who are unable to be enrolled by 96 hours postnatal age [+3]