Status: Not yet recruiting
Prospective Exploratory Study of a Multiomic Blood Biomarker Panel to Predict Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The goal of this prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months is to identify biomarkers to predict the overall occurrence of chronic chemotherapy-induced peripheral neuropathy (CIPN, any grade), in each of two treatment subgroups (taxanes and oxaliplatin). It involves integration of clinical data and plasma multiomic biomarkers (proteomic + metabolomic panel) analyzed via supervised machine learning to identify predictive features of CIPN.
Participants needed: 192
Trial details
Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de BlignyUpdated: Apr 13, 2026
Eligibility criteria
Patients who have received detailed information about the study and have signed,... [+4]
Patients already suffering from neuropathy or chronic neurogenic pain [+4]