Status: Recruiting

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.

Participants needed: 100

Trial details

Age: 18+Biological sex: AllType: ObservationalSponsor: M.D. Anderson Cancer CenterUpdated: Apr 16, 2026Locations: 1

Eligibility criteria

Ages Eligible for Study: 18 Years and above (Adult, Older Adult) [+6]

Status: Not yet recruiting

Assessing DCog Short for Neurotoxicity in CAR-T

The aim of this study is to determine the effectiveness of DCog Short, a self-reporting, iPad-based application tool, in assessing neurotoxicity in participants undergoing CAR-T cell therapy.

Participants needed: 40

Trial details

Age: 18+Biological sex: AllType: InterventionalSponsor: Beth Israel Deaconess Medical CenterUpdated: Feb 11, 2026Locations: 1

Eligibility criteria

participants treated with CART-Cell therapy as described above and therefore at... [+1]

patients < 18 years old [+4]

Status: Recruiting

Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations

This is a randomized open label study in de novo liver transplant recipients that aims to compare the risk of tacrolimus induced tremors with once daily extended-release formulation, Envarsus, versus the twice daily immediate-release formulation. Both formulations of tacrolimus are currently approved for the prevention of rejection in liver transplant patients.

Participants needed: 124

Trial details

Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Jan 2, 2024Locations: 1

Eligibility criteria

Adults aged 18 years or older [+4]

Recipients of prior organ transplant [+7]