No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy

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Review clinical trials related to No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer. This is an multicentre, single Arm, Phase 2 Trial study of Cadonilimab with Cisplatin in the treatment of locally advanced cervical cancer. 29 eligible patients will receive Cadonilimab(10mg/kg, iv., D1, q3w)with Cisplatin ( 75mg/ m2, iv., D2, q3w) for a total of 2-4 cycles before radical surgical treatment.

Participants needed: 29
Trial details
Phase: Phase 2Age: 18-75Biological sex: FemaleType: InterventionalSponsor: The First Affiliated Hospital of Zhengzhou UniversityUpdated: Aug 5, 2025Locations: 1
Eligibility criteria

Female, age ≥18 years; [+5]

Diagnosis of other malignancies within 5 years prior to the first dose (excludin... [+23]