Non-Arteritic Anterior Ischemic Optic Neuropathy

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Review clinical trials related to Non-Arteritic Anterior Ischemic Optic Neuropathy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

This is a phase 3, randomized, multicenter, vehicle-controlled, double-masked study to evaluate the efficacy and safety of intranasal cenegermin compared with vehicle control in adult participants with NAION. Approximately 272 participants who meet all eligibility criteria will be randomly assigned in a 1:1 ratio to receive either cenegermin treatment (Group 1) or the vehicle control (Group 2).

Participants needed: 272
Trial details
Phase: Phase 3Age: 50-80Biological sex: AllType: InterventionalSponsor: Dompé Farmaceutici S.p.AUpdated: Jun 22, 2026Locations: 18
Eligibility criteria

A clinical diagnosis of unilateral NAION in the study eye with symptom onset wit... [+2]

Bilateral NAION or sequential NAION with fellow eye involvement within 6 weeks o... [+5]