Non-segmental Vitiligo

9

Review clinical trials related to Non-segmental Vitiligo. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Learn How Safe ACT-777991 is and How Well it Works in Adults With Non-segmental Vitiligo

The purpose of this clinical trial is to learn how well ACT-777991 works, how safe it is and how well it is tolerated by adults with non-segmental vitiligo. The main question this clinical trial aims to answer is: • Can ACT-777991 help return color to the skin of the face of adults with non-segmental vitiligo? Researchers will compare ACT-777991 to placebo (a look-alike inactive treatment that contains no medicine) to see if ACT-777991 works to treat non-segmental vitiligo. Trial participants will: * Take the trial intervention (either ACT-777991 or placebo) daily for 24 weeks. * Visit the clinic 7 times for check-up and tests.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Idorsia Pharmaceuticals Ltd.Updated: Jun 25, 2026
Eligibility criteria

F-VASI score ≥ 0.3 based on BICR at Screening. [+3]

Clinical diagnosis of other forms of vitiligo (e.g., segmental) or other hypo- o... [+5]

Status: Recruiting

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

The main purpose of this multicenter, randomized, double-blind, placebo-controlled Phase 2b study is to investigate the safety and efficacy of GIA632 in participants with NSV and to identify the optimal dose to be promoted into the confirmatory Phase 3 program.

Participants needed: 210
Trial details
Phase: Phase 2Age: 18-99Biological sex: AllType: InterventionalSponsor: Novartis PharmaceuticalsUpdated: Jun 22, 2026Locations: 33
Eligibility criteria

Signed informed consent must be obtained prior to participation in the study [+5]

Individuals unable or unwilling to follow the study procedures and/or to complet... [+4]

Status: Recruiting

Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients

The primary purpose of this study is to evaluate whether the drug EI-001 can help improve vitiligo symptoms. EI-001 is a novel antibody drug that affects the immune system to decrease uncontrolled inflammation. EI-001 has been investigated in human cell cultures, animal studies, and in a Phase 1 healthy volunteer study. The results so far show that EI-001 is a tolerable and potential new treatment for immune diseases such as vitiligo.

Participants needed: 45
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Elixiron Immunotherapeutics (Hong Kong) Ltd.Updated: Jun 5, 2026Locations: 6
Eligibility criteria

Able to understand and voluntarily sign the informed consent form (ICF). [+8]

Non-eligible skin conditions: Other types of vitiligo (e.g., segmental) or other... [+13]

Status: Recruiting

A Trial of SHR0302 Tablets and SHR0302 Base Gel in Patients With Non-segmental Vitiligo

The study is being conducted to evaluate the efficacy, and safety of SHR0302 tablets as single therapy or in combination with SHR0302 Base gel for patients with non-segmental vitiligo.

Participants needed: 176
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Jiangsu HengRui Medicine Co., Ltd.Updated: Feb 18, 2026Locations: 1
Eligibility criteria

Sign the informed consent form before the clinical trial. [+4]

Subjects diagnosed with segmental, mixed or undifferentiated vitiligo; or subjec... [+11]

Status: Recruiting

Efficacy and Safety Phase II Study of VC005 Tablets in Subjects With Non-segmental Vitiligo

This clinical trial is a multicenter, randomized, double-blind, controlled phase II clinical study

Participants needed: 120
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Jiangsu vcare pharmaceutical technology co., LTDUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

The subject understands and voluntarily signs the informed consent form (ICF) an... [+1]

Pregnant or lactating women, or subjects with pregnancy or lactation plans durin... [+4]

Status: Recruiting

Comparison of Needling and Microneedling Plus Phototherapy in Localized Vitiligo Patients

This randomized controlled trial aims to compare the efficacy of needling versus microneedling, both followed by narrowband UVB therapy, in achieving repigmentation in patients with localized stable non-segmental vitiligo.

Participants needed: 80
Trial details
Phase: Phase 4Age: 15-60Biological sex: AllType: InterventionalSponsor: Khyber Teaching HospitalUpdated: Sep 2, 2025Locations: 1
Eligibility criteria

Both male and female [+2]

Patients with tendency of keloid formation or hypertrophic scarring [+3]

Status: Recruiting

An Open-label Single Center, Proof of Concept Study Evaluating the Efficacy of Roflumilast Foam 0.3% in Pediatric Patients With Non-Segmental Vitiligo (NSV)

An open-label single center, proof of concept study evaluating the efficacy of Roflumilast foam 0.3% in pediatric subjects with Non-Segmental Vitiligo (NSV)

Participants needed: 20
Trial details
Phase: Phase 2Age: 2-18Biological sex: AllType: InterventionalSponsor: Derm Texas, PLLCUpdated: Aug 8, 2025Locations: 1
Eligibility criteria

Male or female subjects aged 2 years but less than 18 years [+7]

Subjects with any serious medical condition or physical examination abnormality... [+13]

Status: Recruiting

ICP-332 in Subjects With Non-segmental Vitiligo

This a phase II/III randomized, double-blind, placebo-controlled, parallel group, adaptive design, multi-center study to evaluate the efficacy and safety of ICP-332 in subjects with non-segmental vitiligo。The study consisted an phase 2 part and an phase 3 part.

Participants needed: 603
Trial details
Phase: Phase 2, Phase 3Age: 12-75Biological sex: AllType: InterventionalSponsor: Beijing InnoCare Pharma Tech Co., Ltd.Updated: Aug 7, 2025Locations: 45
Eligibility criteria

Male or female subjects aged ≥18 years and ≤75 years (Phase II portion). Male or... [+7]

Any of the following vitiligo related medical conditions and other skin diseases... [+3]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients

A 52-Week Study of SYHX1901 tablet in Adults with non-segmental vitiligo.

Participants needed: 144
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: CSPC Ouyi Pharmaceutical Co., Ltd.Updated: Jul 22, 2024Locations: 1
Eligibility criteria

Willing to sign an ICF, able to comprehend and comply with the study procedures. [+4]

Diagnosed as other active depigmentation disease. [+8]