Non-squamous EGFR Wt NSCLC

1

Review clinical trials related to Non-squamous EGFR Wt NSCLC. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

HWK-007-101 is a multicenter, open-label, first-in-human (FIH) Phase 1 study evaluating HWK-007, a protein tyrosine kinase 7 (PTK7)-targeted antibody drug conjugate (ADC), in adult participants with advanced or metastatic solid tumors known to be expressing PTK7. The study employs a sequential dose escalation and dose expansion design without a control group.

Participants needed: 226
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Whitehawk Therapeutics, Inc.Updated: Mar 27, 2026Locations: 12
Eligibility criteria

non-squamous EGFR-Wt NSCLC [+4]

Individual with known or suspected uncontrolled central nervous system (CNS) met... [+8]