Obese Patients With Bariatric Surgery

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Review clinical trials related to Obese Patients With Bariatric Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Bariatric Surgery and Gut Microbiota Changes Over Time

The goal of this observational study is to learn how bariatric surgery affects gut bacteria and gut-related metabolic products over time in adults with obesity. The study includes adults aged 18 to 65 years who are undergoing Roux-en-Y gastric bypass (RYGB) surgery, as well as adults with obesity treated with diet alone and healthy normal-weight adults. The main questions it aims to answer are: How does bariatric surgery change the composition and diversity of gut bacteria over time? How are these changes related to weight loss and improvement of obesity-related health conditions? Researchers will compare people undergoing bariatric surgery with people with obesity treated with diet alone and with healthy normal-weight individuals to see if surgery leads to specific changes in gut bacteria and stool metabolites that are linked to better clinical outcomes. Participants will: Provide stool samples at scheduled time points over 12 months Provide blood samples and undergo routine clinical assessments Take part in follow-up visits to monitor weight, metabolic health, and gastrointestinal symptoms

Participants needed: 100
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Age between 18 and 65 years. [+1]

Treatment with antibiotics within the last 3 weeks, or probiotics/prebiotics wit... [+20]

Status: Not yet recruiting

Intravenous Tranexamic Acid

Tranexamic acid is a promising option for minimizing blood loss in high-risk bariatric surgery patients, particularly in those with obesity, diabetes, and other comorbidities. When used appropriately, TXA can reduce the need for blood transfusions, maintain hemodynamic stability, and lower the incidence of complications related to blood loss.

Participants needed: 128
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Sep 25, 2025Locations: 1
Eligibility criteria

High-risk patients, with obesity, BMI more than 45, [+1]

patients with active thromboembolic disorders. [+1]

Status: Recruiting

Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery

this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score

Participants needed: 60
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Mahmoud Gamal Ahmed ArakeebUpdated: Apr 29, 2025Locations: 1
Eligibility criteria

patients who have a BMI 30-40 kg/m2 [+3]

patients' refusal to participate in the study, [+5]